|We will rebuild, and we will thrive.|
The Anti-Life Equation is something of interest to Darkseid, who has been pursuing it for centuries. According to Granny Goodness, the equation is "
Life − Free Will = Anti-Life". The equation also poses as a threat to the Light's plans, as it would give a major advantage to Darkseid’s faction in their race for global dominance.
Granny Goodness believes that Halo within the Ghost Dimension of the X-Pit is the key to the Anti-Life Equation, which she phrases as "
Ghost Dimension + Halo = Anti-Life". As she finds out and explains, Halo is connected to the source of all life due to being a Motherbox. However, being trapped in an organic body means she lacks the technological safeguards that Metron installed into the non-organic Motherboxes and Fatherboxes. This allows the Ghost Dimension, which has side-effects that are "deleterious to the mind, spirit and body", to "repolarise" the energy coming from Halo, turning her Violet Aura into an Aura of Anti-Life. This Aura prevents Halo from healing from the damage caused by the Ghost Dimension, which it normally would, while causing anyone enveloped in the Aura to obey any commands given. Even after the person is brought out of the Aura, they will still obey for the person ordering them as Helga admits to Granny Goodness that, despite hating her entirely for making her reveal her secrets, she'd still do anything for Granny which the latter believes is due to the Anti-Life.
In the DC comics, the Anti-Life Equation is a theory developed by Darkseid after he learned of the Martian concept of the "Life Equation". Supposedly, the Anti-Life Equation mathematically proves that hope, love, and freedom are all meaningless; exposure to the equation effectively destroys a person's free will. Darkseid finally succeeded in figuring out the Anti-Life Equation, and tried to release it over the Internet during the Final Crisis.